Relaxation Mechanisms of Nitric Oxide Donors, β2-Adrenoreceptor Agonist and Their Synergistic Effect In Vitro in Airway Smooth Muscle: Role of Potassium channels
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چکیده
To be presented, with the assent of the Medical Faculty of the University of Helsinki, for public examination in the big auditorium of the Helsingin yliopiston verkkojulkaisut 4 Kaulitaan ja käännetään, ja kaulitaan ja käännetään Rollout and fold, roll out and fold again Kohta meissä kaikissa asuu pieni lehmä... In everyone of us, there is soon a small cow...
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ASM-024, a Piperazinium Compound, Promotes the In Vitro Relaxation of β2-Adrenoreceptor Desensitized Tracheas
Inhaled β2-adrenoreceptor agonists are widely used in asthma and chronic obstructive pulmonary disease (COPD) for bronchoconstriction relief. β2-Adrenoreceptor agonists relax airway smooth muscle cells via cyclic adenosine monophosphate (cAMP) mediated pathways. However, prolonged stimulation induces functional desensitization of the β2-adrenoreceptors (β2-AR), potentially leading to reduced cl...
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